Pages: 43-46
Published Date:
[ Abstract ]
Abstract: Background: diabetes is a metabolic disorder in which the body is not able to make full use of sugar and is associated with many complications. The most important of which dyslipidemia can be pointed out which is one of the most important signs of cardiovascular diseases. In general, in the world, especially in recent years, the general trend has been rising in the use of herbal medicines which are rich sources of natural antioxidants. The purpose of this study was to investigate the effects of hydroalcoholic extract of dill plant and Rosa Canina in reducing sugar and fat in diabetic patients’s blood. Materials and methods: In this study, 40 adult male rats, weighing 200-250 g were divided into five groups of eight each: Group I served as control rats (non-diabetic group), and Group II (diabetic control) received alloxan monohydrate in a dose 120 mg / kg during six days on alternate days, and Groups III and IV, received alcoholic extract of dill and Rosa Canina as 300 mg / kg (by intraperitoneal injection) and Group VI received 150 mg / kg equally from each extract with overall volume 300 mg / kg for 10 days. At the end of treatment after blood sample collection, blood sugar content, cholesterol, triglycerides, LDL, HDL were measured. Results: The results showed that Rosa Canina Hydroalcoholic extract and dill hydroalcoholic extract significantly reduced (p <0.05) glucose, cholesterol, triglycerides, LDL, and significantly increased HDL (p < 0.05). On the other hand, the effect of dill hydroalcoholic extract was more than that of Rosa Canina and combining the two extracts had a greater impact than individual extracts. Conclusions: It seems, combining the two extracts in diabetic patients, is a more effective procedure in controlling blood sugar and fat.
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